Autologous rosette formation by human blood monocyte‐derived macrophages and lymphocytes
نویسندگان
چکیده
منابع مشابه
Rosette formation between human lymphocytes and sheep erythrocytes. Inhibition of rosette formation by specific glycopeptides.
Rosette formation with unsensitized sheep erythrocytes is a characteristic of human thymus dependent lymphocytes. Release of glycopeptides from the sheep erythrocyte by trypsin reduces rosette formation. These tryptic glycopeptides inhibit rosette formation by untrypsinized sheep erythrocytes; this suggests that rosetting is mediated by erythrocyte surface glycopeptides. To investigate the mole...
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Rosette formation, a phenomenon in which a leucocyte becomes surrounded by a cluster of erythrocytes (Fig. 1) may occur in a variety of circumstances. For example, when lymphocytes from an animal which has been immunized against erythrocytes of another species are mixed with a suspension of the foreign red cells, a certain proportion of the lymphocytes will form rosettes (Biozzi, Stiffel, Mouto...
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In the majority of patients with rheumatoid arthritis the immune response is most readily detected as a production of rheumatoid factors, IgM antibodies, which agglutinate to high titre erythrocytes coated with IgG antibodies from man, rabbit, or sheep, etc. Generally, only low titres of rheumatoid factors are found in nonrheumatoid individuals. Bach, Delrieu, and Delbarre (1970a, b) described ...
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We had previously found in autologous human leukocyte cultures, in which dead neutrophils phagocytosis by macrophages occur, macrophages and T CD4 lymphocytes perform a selective cell-cell interaction showing many figures of either one, two or several T- lymphocytes adhering to a central macrophage were seen. Considering that antigen presentation would be necessary for the formation of these im...
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can exert potent suppressor activity regardless of their phenotypes of OKT4+ and OKT8+ antigens, and fail to help B cell differentiation; suppressor function mediated by these cells is radiosensitive; moreover, receptors for autologous erythrocytes may constitute either the interleukin 2 (IL2) receptors themselves or a component of an IL2 receptor-effector complex involved in modulating the gro...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1999
ISSN: 0361-8609,1096-8652
DOI: 10.1002/(sici)1096-8652(199904)60:4<285::aid-ajh6>3.3.co;2-1